Medical Research Updates ⌠MRU⌡. Case Report
MRU 2024; Vol.1(Issue2): 1-4 ISSN 200XX |
https://www.mruj.online
1
Ectopic Twin Pregnancy: A case report
Nawal Ali Ahmed Mohamed
1
, Haitham Abdalla Ali Ismail1, Ahmed Elnour Adam Zakaria1, Abuelez Hassan
Ibrahem Abdalla2
1Department of Obstetrics and Gynecology, Faculty of Medicine & Health Sciences, University of Kordofan.
2Department of Community Medicine, Faculty of Medicine & Health Sciences, University of Kordofan
ABSTRACT
Spontaneous pregnancy of a live twin ectopic pregnancy is very rare. The obstetrics and gynecology department
at El Obeid Teaching Hospital in Sudan discovered this twin ectopic pregnancy. A prime-aged woman, p1+1, had
five days of lower abdominal pain. She also reported a seven-week menstrual stop and a positive serum HCG test.
Ultrasounds showed an ectopic twin pregnancy in the right adnexa and an embryonic-free uterine cavity. She
performed an emergency laparotomy after seeing a considerable increase in discomfort and sensitivity while
prepping the patient for surgery. The patient with hemoperitoneum and right ruptured twin pregnancy is
improving throughout follow-up. There is no definitive recommendation for treating ectopic twin pregnancies.
Keywords: Ectopic pregnancy, conception, obstetric emergency
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Correspondence to: Nawal Ali Ahmed Mohamed, Faculty of Medicine & Health Sciences, University of
Kordofan, Sudan Email: nawalaliahmed79@gmail.com, Mobile: +249912661510
Cite this article: Mohamed NAA, Ismaail HAA, Zakaria AAA, Ibrahim AAH. Ectopic Twin Pregnancy: A case report.
Medical Research Updates 2024;1(2): 1-5. https://www.mruj.online/current-issue
INTRODUCTION
Ectopic pregnancies are the leading cause of
maternal mortality in the first trimester, with an
incidence of 5%10% of all pregnancy-related
deaths. Diagnosis of ectopic pregnancies is difficult
due to clinical mimics and non-specific symptoms
of abdominal pain and vaginal bleeding [1]. Ectopic
pregnancy occurs when a fertilized ovum implants
outside of the uterine cavity. Risk factors include a
history of pelvic inflammatory disease, cigarette
smoking, fallopian tube surgery, previous ectopic
pregnancy, and infertility. Serial beta human
chorionic gonadotropin levels, serial
ultrasonography, and, at times, uterine aspiration
can be used to arrive at a definitive diagnosis.
Treatment of a diagnosed ectopic pregnancy
includes medical management with intramuscular
methotrexate, surgical management via
salpingostomy or salpingectomy, and, in rare cases,
expectant management. A woman who has been
diagnosed with an ectopic pregnancy should have
surgery right away if she has peritoneal signs or
hemodynamic instability, if her initial beta human
chorionic gonadotropin level is high, if
ultrasonography shows fetal cardiac activity
outside of the uterus, or if medical management is
not an option [2, 3]. Given the rarity of twin ectopic
pregnancies, it is important to address the question
of where they originate and whether they are
similar or not. In this report, we dealt with a case of
Medical Research Updates ⌠MRU⌡. Case Report
MRU 2024; Vol.1(Issue2): 1-4 ISSN 200XX |
https://www.mruj.online
2
twin ectopic pregnancy, which was detected by
chance before the development of complications.
CASE REPORT
A 37-year-old woman from Alfola city, West
Kordofan state, approximately 289 kilometers
from El-Obeid city, presented to our clinic with a
five-day history of left-sided abdominal pain and a
7-week history of amenorrhea. She was born via
cesarean section prior to the age of 20, is G3 P 1+1,
and has a prior history of miscarriage during the
third trimester of a twin pregnancy. She presented
herself at our obstetrics and gynecology facility
subsequent to receiving a diagnosis of an ectopic
pregnancy from a sonographer in her place of
residence. There was no pain, vaginal bleeding, or
gastrointestinal distress that she reported. Her
vital signs were within normal range, and the
examination revealed a soft abdomen and a small
tender lesion in the right iliac fossa. All other tests
came back normal, except for the serum HCG level,
which was positive. Images 1 and 2 show a healthy
ectopic twin pregnancy in the right adnexa,
whereas image 3 shows an empty uterine cavity.
Following the patient's counseling, an appointment
for surgery was set up. During the patient's
preoperative preparations, she complained of
severe abdominal pain and sweating. Upon
examination, the doctor found hemoperitoneum
and a ruptured right ectopic pregnancy; the patient
underwent a right salpingectomy (see Image 4).
The patient's left tube was attached to the posterior
uterine wall and had an abnormal fimbrial end,
suggesting pelvic inflammatory disease. The
patient's postoperative recovery was smooth, and
she was counseled regarding her fertility.
DISCUSSION
Ectopic twin pregnancy is a rare and hazardous
first-trimester pregnancy condition. To avoid
maternal morbidity and mortality, a high index of
suspicion and rapid intervention are required.
Unilateral tubal twins are a rare diagnosis,
occurring in approximately one in every 200,000
2,500,000 spontaneous births [4,5].
Obstetric abdominal pain poses a challenging
diagnostic challenge in the emergency department
(ED) due to the extensive list of differential
diagnoses that must be considered and the
potential for atypical signs and symptoms
associated with each disease, which may be
exacerbated by the patient's pregnancy. However,
emergency physicians (EPs) encounter constraints
on investigative imaging modalities as a result of
the mandate to minimize embryonic radiation
exposure. In a timely manner, EPs must address
this diagnostic challenge while balancing maternal
and fetal outcomes, as any delays in decision-
making at the ED could endanger the life and well-
being of both the mother and the fetus. Ectopic
pregnancy and acute appendicitis are two common
causes of abdominal distress in pregnant women
who present to the emergency department. By the
tenth week of gestation, identification of the latter
is almost certain [6].
The fallopian tube is the most prevalent location for
ectopic pregnancy. The management of such
instances is not well defined. The surgical
technique consisting of a salpingectomy or
salpingostomy is the most common in the case of a
desire to sustain an intrauterine pregnancy. Such a
treatment is beneficial, but it has the potential
dangers associated with surgery; therefore, in
Medical Research Updates ⌠MRU⌡. Case Report
MRU 2024; Vol.1(Issue2): 1-4 ISSN 200XX |
https://www.mruj.online
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certain circumstances, expectant management
appears fair [7].
The risk of rupture is higher in twin ectopic
pregnancies, and rupture is anticipated to occur in
3050% of cases, despite the fact that the
morbidity and mortality associated with singleton
ectopic pregnancies have greatly decreased. For
these pregnancies, surgical intervention remains
the cornerstone of care [8].
In conclusion, for ectopic pregnancies, healthcare
personnel should have a high level of clinical
suspicion. While unilateral tubal twin ectopic
pregnancies are uncommon, transvaginal
ultrasonography can detect them. Laparoscopic
salpingostomy is a safe and effective procedure for
unilateral tubal twin pregnancy with a quick
recovery time.
ACKNOWLEDGMENTS
We would like to thank Professor Ahmed Ajab
eldour for his valuable assistance and guidance, as
well as the theater personnel at obstetric
department in El-Obeid Teaching Hospital for their
care and support.
REFERENCES
1- Mullany K, Minneci M, Monjazeb R, C Coiado O.
Overview of ectopic pregnancy diagnosis,
management, and innovation. Womens Health
(Lond) 2023; 19: 17455057231160349. doi:
10.1177/17455057231160349.
2- Hendriks E, Rosenberg R, Prine L. Ectopic
Pregnancy: Diagnosis and Management. Am Fam
Physician 2020;101(10):599-606.
3- Tonick S, Conageski C. Ectopic Pregnancy. Obstet
Gynecol Clin North Am 2022;49(3):537-549. doi:
10.1016/j.ogc.2022.02.018.
Image 1: Image of gestational sac contains two fetal
poles in the Rt Fallopian tube.
Image2: Two fetal poles and yolk sac within the RT
fallopian tube besides the empty uterine cavity.
Medical Research Updates ⌠MRU⌡. Case Report
MRU 2024; Vol.1(Issue2): 1-4 ISSN 200XX |
https://www.mruj.online
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Image 3: empty uterin cavity with thick
endometrium.
Image 4: Two embryonic fetuses and their
placental tissue.
4- Samha R, AlAwad Y, Wardeh AM, Ibrahem AM, Abo
Moughdeb AK. A unilateral twin ectopic pregnancy
in the fallopian tube: A rare case report. Int J Surg
Case Rep 2023; 111:108833. doi:
10.1016/j.ijscr.2023.108833.
5- Zhang Y, Lu X, Wang X, Wu X, Jing X, Cui X. Rare
Unilateral Twin Ectopic Pregnancy After Frozen
Embryo Transfer: A Case Report and Literature
Review. Int Med Case Rep J 2023; 16:731-737. doi:
10.2147/IMCRJ.S409492.
6- Seak CJ, Goh ZNL, Wong AC, Seak JC, Seak CK.
Unilateral live twin tubal ectopic pregnancy
presenting at 12 weeks of gestation: A case report.
Medicine (Baltimore) 2019; 98(38):e17229. doi:
10.1097/MD.0000000000017229.
7- Młodawski J, Kardas-Jarząbek A, Młodawska M,
Świercz G. Conservative Management of
Heterotopic Pregnancy: A Case Report and Review
of Literature. Am J Case Rep 2023 8;24:e940111.
doi: 10.12659/AJCR.940111.
8- Martin A, Balachandar K, Bland P. Management of a
spontaneously conceived live unilateral twin
ectopic pregnancy in Australia: A case report. Case
Rep Womens Health 2021; 30:e00300. doi:
10.1016/j.crwh.2021.e00300.