Medical Research Updates ⌠MRU⌡

MRU 2024; Vol.2(Issue1): 7-10 ISSN 00000 | DOI: 00000000000 ORIGINAL RESEARCH ARTICLE

Are Chronic lymphocytic leukemia blood parameters differing from Other leukemias

subtypes

Ekhlas Alrasheid Abuelfadol1, Mahadi Musa Mohammed Abdalla2, Mohieldin Elsayid3, Ahmed Abdula

Agabeldour4

1Department of Hematology, Faculty of Medical Laboratory Sciences, Kordofan University, El-Obeid, Sudan.

2Ministry of Health, El-Obeid Obstetrics and Gynecology, El-Obeid, Sudan.

3King Abdullah International Medical Research Center (KAIMRC), King Saud bin Abdulaziz University for

Health Sciences (KSAU-HS), King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi

Arabia.

4Department of Pathology, Faculty of Medicine, Kordofan University, El-Obeid, Sudan.

ABSTRACT

Background: Adults widely acknowledge CLL as a prevalent lymphoproliferative disease, a

hematological malignancy. Thus, the objective of this study was to assess potential differences in blood

parameters among CLL and other subtypes of leukemia. Methodology: The current study utilized

lymphoma data acquired from El-Obeid Oncology Center. The document included data on lymphoma

patients diagnosed between January 2018 and January 2020. The sample included a total of one

hundred patients, of which sixty-one had CLL and forty-nine did not. The traditional BM aspiration

diagnosis for the patient was lymphoma. Results: Within this series, CLL was the most prevalent form

of cancer, followed by CML, NHL, MM, HL, and various other types, making up 61%, 17%, 11%, 6%,

and 3% of cases, respectively. All cases of CLL, MM, and NHL exhibited BM hypercellularity.

Megakaryopoiesis was not observed in ten cases, which consisted of eight (80%) CLL patients and two

(20%) MM patients. We observed megakaryopoiesis in 43 instances, with 60.5% of the cases being CLL

and 30.2% being CML. There were only two instances where CLL showed a decrease in

megakaryopoiesis. We found 34 patients with depressed erythropoiesis. This included CLL in 59% of

cases, CML in 26.5% of cases, and MM in 8.8% of cases. Conclusion: CLL demonstrates a unique set of

hematological parameters when compared to other blood malignancies. CML demonstrates a pattern

that is similar to CLL in different hematological parameters, such as the overall count of white blood

cells.

Keywords: leukemia, lymphoma, blood cancer, hematological parameters, Sudan

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Correspondence to: Ekhlas Alrasheid Abuelfadol, Email: ekhlas1988@gmail.com

Cite this article: Abuelfadol EA, Abdalla MMM, Elsayid M, Agabeldour AA. Medical Research Updates 2024;2(1): 1-10. DOI: 0000